VINCENT SURGICAL ARTS + VINCENT LONGEVITY INSTITUTE
EBOO
Extracorporeal Blood Oxygenation, Ozonation & Filtration
OPTIMIZE YOUR BLOOD. CHANGE THE CELLULAR ENVIRONMENT.
EBOO is an advanced physician-directed extracorporeal therapy in which blood is continuously circulated through a treatment circuit, filtered, exposed to a precisely controlled oxygen-ozone mixture and returned to the patient. Our protocols integrate EBOO with precision longevity medicine, perioperative optimization and recovery.
EBOO Ozone Therapy
The Vincent Approach
EBOO is not treated as an isolated procedure. We integrate blood treatment with cardiovascular and metabolic assessment, targeted intravenous support, glutathione, nutrition, recovery therapies and longitudinal biomarker tracking.
Why Patients Choose EBOO
Circulation
Support healthy circulation, microvascular blood flow and tissue oxygen delivery
Redox defense
Promote adaptive redox signaling and endogenous antioxidant defenses
Mitochondrial resilience
Support mitochondrial resilience and cellular energy pathways
Immune balance
Support balanced inflammatory and immune signaling
Recovery & performance
Complement longevity, recovery and performance programs
Integrated longevity
Integrate naturally with Therapeutic Plasma Exchange, hyperbaric oxygen and photobiomodulation
What Happens During EBOO?
A large volume of circulating blood is treated continuously through an extracorporeal circuit. The goal is to combine filtration with controlled oxygen-ozone exposure, creating both direct blood-treatment effects and a short, controlled redox signal that can activate the body’s own adaptive defense systems.
Blood
Blood enters the treatment pathway.
Extracorporeal circuit
Continuous circulation through an external circuit.
Filtration
Filtration of circulating blood.
Oxygen / ozone
Precisely controlled oxygen-ozone exposure.
Full spectrum UV
Optional: when incorporated into the protocol.
Return to patient
Treated blood returns to the patient.
Cellular & vascular response
The adaptive response described above.
Six Biological Targets of EBOO
Redox & NRF2 signaling
A controlled oxidative signal can activate nuclear factor erythroid 2-related factor 2 (NRF2), supporting heme oxygenase-1, glutathione-related enzymes and endogenous antioxidant defenses.
Circulation & endothelium
Supports vascular signaling, blood rheology, microcirculation and efficient delivery of oxygen and nutrients to tissues.
Mitochondrial resilience
Adaptive redox signaling interfaces with cellular energy-sensing pathways involved in mitochondrial maintenance, stress resistance and metabolic flexibility.
Inflammatory signaling
Supports a more balanced inflammatory environment through redox-sensitive signaling networks, including pathways that regulate nuclear factor kappa B activity.
Immune resilience
Ozone-mediated redox signaling and, when used, ultraviolet blood treatment provide complementary inputs to immune and cellular defense pathways.
Filtration of circulating blood
Extracorporeal filtration adds a physical blood-treatment component that is distinct from the plasma removal and replacement performed during Therapeutic Plasma Exchange.
The Hormetic Concept
Think of EBOO as a controlled biological training signal: a brief, physician-directed redox challenge is followed by an adaptive response designed to strengthen endogenous cellular defense and recovery pathways.
A Multi-System Optimization Strategy
EBOO fits naturally into a precision longevity program because the blood, vascular system, mitochondria, immune system and redox environment are interconnected. Treatment goals are individualized to the patient.
Potential Areas of Benefit
- Energy, vitality and recovery support
- Microcirculation and vascular optimization
- Endothelial and cardiometabolic support
- Mitochondrial resilience and metabolic flexibility
- Healthy redox balance and antioxidant defense
- Balanced inflammatory signaling
- Immune resilience
- Exercise and performance recovery
- Healthy-aging and longevity programs
- Support during physician-directed chronic inflammatory, environmental-exposure and post-infectious optimization programs
Who We Commonly Consider for EBOO
Proactive longevity
Patients pursuing proactive longevity and performance optimization
Surgical optimization
Patients preparing for or recovering from surgery
TPE programs
Patients receiving a series of Therapeutic Plasma Exchange treatments
Individual evaluation
Patients with high inflammatory or oxidative burden identified during evaluation
Cardiometabolic focus
Patients focused on cardiovascular, metabolic or endothelial optimization
Resilience & recovery
Patients seeking a physician-directed strategy for resilience, recovery and healthy aging
Precision, Not One-Size-Fits-All
The treatment plan is selected after clinical review. EBOO can be used as a stand-alone optimization treatment or integrated into a broader program based on goals, biomarkers and recovery needs.
EBOO Before & After Surgery
At Vincent Surgical Arts, EBOO may be incorporated into a comprehensive preoperative and postoperative optimization program. Surgical recovery requires circulation, oxygen delivery, mitochondrial energy production, controlled inflammatory signaling, antioxidant capacity and adequate nutritional building blocks.
PREPARE
Before surgery
- Support microcirculation and tissue oxygen delivery
- Promote healthy endothelial and redox signaling
- Support endogenous antioxidant defenses
- Support mitochondrial resilience and cellular energy production
- Prepare the body for the metabolic demands of surgery and healing
RECOVER & REBUILD
After surgery
- Support tissue recovery and wound-healing biology
- Support circulation during the postoperative period
- Support the body's inflammatory and oxidative response to surgery
- Support mitochondrial energy needs during repair
- Integrate with nutrition, mobility and physician-directed recovery protocols
PREPARE → OPERATE → RECOVER → REBUILD
Our surgical optimization philosophy begins before the first incision and continues beyond the operating room.
Integrated Recovery Options
Depending on the procedure and patient, EBOO may be combined with hyperbaric oxygen therapy, photobiomodulation/red-light therapy, intravenous nutrient therapy, glutathione, nutrition optimization and individualized regenerative protocols.
INTEGRATED EXTRACORPOREAL MEDICINE
EBOO + Therapeutic Plasma Exchange (TPE)
Therapeutic Plasma Exchange (TPE) and EBOO treat the circulating environment in fundamentally different and potentially complementary ways.
TPE — REMOVE & REPLACE
Therapeutic Plasma Exchange removes a substantial portion of plasma and replaces it with an appropriate replacement solution. The focus is reduction of circulating plasma burden and renewal of the plasma environment.
EBOO — FILTER, OXYGENATE & SIGNAL
EBOO treats circulating blood through filtration and controlled oxygen-ozone exposure, providing a different biological stimulus centered on blood treatment, vascular function, redox signaling and cellular adaptation.
The Vincent Sequencing Strategy
TPE → EBOO → TPE → EBOO → TPE
REMOVE → RECOVER → SIGNAL → REPEAT
Between TPE sessions, EBOO can provide a different type of extracorporeal intervention without simply repeating the same biological strategy. This creates a broader program for patients pursuing longevity optimization, reduction of circulating burden, recovery or complex physician-directed care.
Why Combine Modalities?
- TPE targets the plasma compartment through removal and replacement
- EBOO treats circulating blood and delivers a controlled redox signal
- Intravenous and glutathione support can be layered around treatments
- Hyperbaric oxygen and photobiomodulation can add tissue-oxygenation and mitochondrial support
- Serial biomarker assessment allows the program to remain individualized
The Vincent Experience
More Than an EBOO Treatment
Our goal is to make extracorporeal treatment comfortable, highly personalized and integrated with the rest of the patient's longevity or surgical-recovery program.
During treatment
- Comfort-focused treatment environment with physician oversight
- Optional Hydrafacial, microneedling and selected medical-spa treatments when appropriate
- Facial and scalp massage options
- Celluma photobiomodulation / red-light therapy
- Individualized hydration and recovery support
Before & after treatment
- Targeted oral nutrition and supplementation
- Individualized intravenous nutrient and mineral support
- Glutathione support, commonly used after treatment when appropriate
- Hydration, protein and recovery optimization
- Coordination with TPE, hyperbaric oxygen, photobiomodulation and other Vincent protocols
Precision Longevity Medicine
Measure. Treat. Reassess.
EBOO is most powerful when it is part of a measured strategy. Vincent Longevity Institute can pair treatment with advanced cardiovascular, metabolic, body-composition and biological-aging assessment to help personalize the overall program.
Measurement May Include
- Inflammatory and cardiometabolic biomarkers
- Advanced lipid and vascular-risk assessment
- Endothelial and cardiovascular testing
- Body composition and functional performance testing
- SystemAge biological and organ-aging assessment
- Environmental and toxin-burden testing when clinically appropriate
- Longitudinal reassessment to guide the next phase of care
The integrated pathway
ASSESS → PERSONALIZE → EBOO / TPE / RECOVERY THERAPIES → REASSESS → OPTIMIZE
The objective is not simply to perform a procedure. It is to improve the biological environment in which the patient’s cells, tissues and organs function.
Frequently Asked Questions
How long does EBOO treatment take?
Treatment time varies according to the protocol and equipment used. Many EBOO sessions last approximately 60–90 minutes. Your provider will discuss the expected treatment time during your consultation.
Does EBOO require downtime?
Many patients can return to normal activities following treatment, although individual responses vary. Your provider will give you personalized post-treatment instructions based on your health and treatment protocol.
How many EBOO treatments will I need?
There is no single treatment schedule appropriate for every patient. Your recommended number and frequency of sessions will depend on your health history, goals, response to treatment, and your provider’s clinical assessment.
Who is a candidate for EBOO?
Because EBOO involves extracorporeal blood circulation and IV access, candidacy requires more than simply choosing the treatment from a menu. Your provider will review your health history, current medications, wellness goals, and other relevant factors to determine whether treatment is appropriate for you. EBOO is not suitable for everyone.
Is EBOO the same as dialysis?
No. Both involve extracorporeal circulation and may look somewhat similar because blood travels through external tubing and filtration equipment. However, dialysis is an established medical treatment used to perform critical functions normally handled by impaired kidneys. EBOO is a different procedure involving blood filtration and controlled oxygen-ozone exposure.
Is EBOO FDA approved?
Ozone therapy, including EBOO, is not FDA-approved for the diagnosis, treatment, cure, or prevention of disease. Research into extracorporeal blood ozonation exists, but evidence remains limited and continues to evolve.